What is 10-OH-HHCP? Molecular formation and effects
10 -OH-HHCP is a hydroxylated derivative of the cannabinoid HHCP, a more potent version of HHC. This cannabinoid, although present in low quantities in the cannabis plant, is mainly produced (semi)synthetically by the hydrogenation of CBD or terpenes. HHCP, and therefore its derivative 10-OH-HHCP, is characterized by a longer alkyl chain than traditional HHC, which may impact how it interacts with the endocannabinoid system (ECS).
Formation of 10-OH-HHCP
10-OH-HHCP is formed through the oxidation of HHCP by the enzyme cytochrome P450, present mainly in the liver. This biochemical process results in the addition of a hydroxyl group (-OH) at the tenth position of the molecule, which increases its solubility and can change the way this substance interacts with receptors in the human body. This chemical modification also influences the effects that 10-OH-HHCP can produce on the body, potentially by amplifying its psychoactive properties.
What are the effects of 10-OH-HHCP?
Research on 10-OH-HHCP is still in its infancy, limiting our precise understanding of its effects. However, based on similar cannabinoids, it is possible that 10-OH-HHCP mimics the cannabimimetic activity of THC and other derivatives. This cannabinoid may have a strong affinity for the CB1 receptors of the endocannabinoid system, thus producing psychoactive effects. Consumers may experience feelings of relaxation, euphoria, altered perception, or even an increase in appetite.
Like other hydroxylated cannabinoids, it is possible that 10-OH-HHCP is metabolized in the liver by cytochrome P450, generating several metabolites whose impact has not yet been fully explored. These metabolites, combined with the method of administration, influence the duration and intensity of the effects experienced. For example, oral administration could result in greater conversion to inactive metabolites compared to vaporization or sublingual consumption.
In terms of bioavailability, hydroxylated derivatives, such as 10-OH-HHCP, tend to be rapidly metabolized and eliminated by the body, which may shorten the duration of effects. It is crucial to emphasize that current research on 10-OH-HHCP is still insufficient, and additional studies are needed to better understand how it works.
Side effects and potential risks of 10-OH-HHCP
Although the precise side effects of 10-OH-HHCP are not yet well documented, similar effects to other psychoactive cannabinoids can be expected. Side effects may include:
- Dry mouth
- Red eyes
- Increased heart rate
- Drowsiness
- Headache
- Unpleasant psychological effects (anxiety, paranoia, hallucinations)
- Insomnia
- Dizziness
These effects may vary depending on several factors such as health status, metabolism, user sensitivity, dose consumed, and method of administration. It is also possible that new side effects will be discovered as additional studies are conducted on this compound.
Another important point concerns (semi)synthetic products, which are generally more potent than natural cannabinoids. This increased potency increases the risk of overdose, which can lead to unpleasant experiences, often referred to as a “bad trip.” Synthetic products are also associated with purity and safety risks, as legislation surrounding these cannabinoids remains unclear in many countries. This can make it difficult to ensure product quality and safety.
This is why it is essential to always buy from reputable sellers and verify that their products have been tested by independent laboratories. Some sellers publish “Certificates of Analysis” (COAs) directly on their sites for each product, which allows consumers to verify composition and purity.
Comparison between 10-OH-HHCP and 10-OH-HHC
10 -OH-HHC , first isolated in 2015, is another hydroxylated derivative, but this time of HHC. How do these two compounds compare?
| Characteristic | 10-OH-HHCP | 10-OH-HHC |
|---|---|---|
| Specifications | Derived from HHCP with an added hydroxyl group (-OH) | Derivative of HHC with an added hydroxyl group (-OH) |
| Effects | Euphoria, relaxation, increased appetite | Euphoria, relaxation, increased appetite |
| Side effects | Dry mouth, red eyes, anxiety, etc. | Dry mouth, red eyes, anxiety, etc. |
| Legal status | Gray area in most countries | Gray area in most countries |
| Products available | Vapes, flowers, pre-rolls, hash, candies | Vapes, flowers, pre-rolls, hash, candies |
The two compounds share many similarities in effects and usage, but 10-OH-HHCP may have slightly greater potency due to its chemical structure. Products based on these two cannabinoids come in various forms: vapes, infused flowers, pre-rolls, candies, and sometimes even hash.
What 10-OH-HHCP products are available?
Although studies on the effects and mode of action of 10-OH-HHCP are still limited, several products are already available on the market. The most common are:
- 10-OH-HHCP Vapes : These vapes allow you to inhale the compound in vapor form, often available in disposable versions or with replaceable cartridges.
- 10-OH-HHCP Infused Flowers : Cannabis flowers infused with 10-OH-HHCP distillate.
- 10-OH-HHCP Pre-Rolled : Pre-packaged joints containing infused flowers.
- 10-OH-HHCP Hash : Hash infused with this cannabinoid.
- 10-OH-HHCP Candies : Gummies containing 10-OH-HHCP.
However, it is crucial to remember that these compounds are potentially more potent than natural cannabinoids, increasing the risk of overdose and intoxication. Therefore, it is strongly recommended not to drive or operate machinery after consuming 10-OH-HHCP products.
In conclusion, although 10-OH-HHCP offers new insights into the world of (semi)synthetic cannabinoids, much remains to be learned about its effects, metabolism and potential risks. If you choose to try it, be aware of potential side effects and make sure you always buy from trusted, tested sources.